Guitar Hero aura droit à un second volet sur PS2, et pour novembre. Il sera toujours question d'appuyer au bon moment sur cinq touches de la guitare ou de faire vibrer "les cordes" afin de garder le rythme et, en autre nouveauté, ce nouvel épisode proposera plusieurs types de guitares. Parmi les 55 morceaux proposés, on retrouvera du rock, du heavy metal ou de l'alternative. Et un mode deux joueurs, pour renforcer la durée de vie du soft.

1 - Opening Licks
# Mötley Crüe - Shout at the Devil
# Danzig - Mother
# Cheap Trick - Surrender
# Wolfmother - Woman
# Spinal Tap - Tonight I'm Gonna Rock You Tonight

2 - Amp-Warmers
# Kiss - Strutter
# Nirvana - Heart-Shaped Box
# The Police - Message in a Bottle
# Van Halen - You Really Got Me
# Kansas - Carry on Wayward Son

3 - String-Snappers
# Foo Fighters - Monkey Wrench
# Alice in Chains - Them Bones
# Iggy Pop and the Stooges - Search and Destroy
# Pretenders - Tattooed Love Boys
# Black Sabbath - War Pigs

4 - Thrash and Burn
# Warrant - Cherry Pie
# Butthole Surfers - Who Was in My Room Last Night
# Mathew Sweet - Girlfriend
# The Rolling Stones - Can't You Hear Me Knockin'
# Guns N' Roses - Sweet Child O' Mine

5 - Return of the Shred
# Rage Against the Machine - Killing in the Name
# Primus - John the Fisherman
# Sword - Freya
# Thin Lizzy - Bad Reputation
# Aerosmtih - Last Child

6 - Relentless Riffs
# Heart - Crazy on You
# Stone Temple Pilots - Tripping on a Hole in a Paper Heart
# Stray Cats - Rock This Town
# Allman Brothers - Jessica
# Jane's Addiction - Stop

7 - Furious Fretwork
# Anthrax - Madhouse
# Living End - Carry Me Home
# Lamb of God - Laid to Rest
# Reverend Horton Heat - Psychobilly Freakout
# Rush - YYZ

8 - Face-Melters
# Avenged Sevenfold - Beast and the Harlot
# Suicidal Tendencies - Institutionalized
# Dick Dale - Misirlou
# Megadeth - Hangar 18
# Lynyrd Skynyrd - Free Bird